Decoding life sciences

Echoing life narratives

Single Cell ATAC Sequencing (scATAC-seq)

Single-cell ATAC sequencing (scATAC-Seq) enables researchers to capture the chromatin accessibility profiles of tissues at single-cell resolution. By analyzing these profiles, scientists can uncover how tissues and individual cell types change during disease progression or respond to external stimuli and compounds through alterations in chromatin accessibility.

Applications

  • Identification of cell types through chromatin accessibility patterns

  • Analysis of cell states and regulatory dynamics

  • Investigation of developmental processes and disease mechanisms

Advantages

  • Advanced technology and instruments

    Utilizes cutting-edge single-cell ATAC-Seq technology to detect open chromatin regions and identify single-cell transcriptionally active regulatory elements.

    Extensive experience

    Each channel supports a capacity of 500 to 10,000 nuclei.

  • High capture efficiency

    Achieves a nuclear capture rate of up to 65%, ensuring high-quality data output and reliable downstream analysis.

    Reliable and fast turnaround time

    A dedicated project manager ensures that results are delivered within 30 business days of sample quality verification.

Sample Requirements


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Note: Sample amounts are provided for reference only.  For detailed information, please contact us with your customized requests.

Bioinformatics Analysis Pipeline

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DNA Sequencing
LC Sciences provides a variety of fast, comprehensive DNA sequencing solutions, including exome, whole-genome, whole-genome bisulfite, and reduced representation bisulfite sequencing.
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Microbial Sequencing
LC Sciences provides a fast, comprehensive microbial Sequencing solution including: 16S/18S/ITS Amplicon Sequencing, 5R 16S Amplicon Metagenomic Sequencing, Shotgun Metagenomic Sequencing.
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RNA Sequencing
LC Sciences offers a range of rapid and comprehensive RNA sequencing solutions, including poly-A RNA, micro RNA, total RNA, circRNA, m6A RNA, and more.
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Epigenomics
LC Sciences provides specialized epigenomics services, including Whole Genome Bisulfite Sequencing (comprehensive single-base resolution DNA methylation analysis), Reduced Representation Bisulfite Sequencing (targeted CpG-rich region study with lower cost), ATAC-seq (chromatin accessibility and regulatory element investigation), and CUT&Tag (high-resolution chromatin profiling for small/single-cell samples).
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Single Cell Sequencing
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Proteomics & Metabolomics
LC Sciences is focused on providing scientific researchers with more minute and precise protein expression-related services, including olink proteomics.
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Pre-made Library Sequencing
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Additional Services
Our portfolio of additional services includes Bioinformatic Services, Oligomix, MicroRNA Profiling Microarray, DNA/RNA Aptamer Microarray, Epitope Mapping, and Kinase Profiling. These services are designed to support various aspects of molecular research and biomolecular analysis, providing comprehensive solutions tailored to your specific scientific needs.
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