The human exome is estimated to contain approximately 180,000 exons, which constitute about 1% of the human genome, or roughly 30 megabases. The objective of this approach is to identify functional variations responsible for both Mendelian and common diseases while accounting for the high costs associated with whole-genome sequencing and the need to maintain high sequencing depth. Therefore, whole-exome sequencing (WES) represents a less costly yet still highly effective alternative to whole-genome sequencing (WGS).
Applications
Cancer research
Genetic disease screening
Human population studies
Discovery of biomarkers and therapeutic targets
Advantages
Quality services
We have Twist exome probes available, and we can provide excellent service.
Extensive experience
We have reliable sample processing capabilities and have successfully extracted tens of thousands of samples of various types, including blood, tissue, FFPE, and swabs.
Specialist team
Our team of experienced experts provides assistance with experimental design and data interpretation.
Reliable and fast turnaround time
A dedicated project manager will be assigned, and results will be delivered within 15 business days after sample quality verification.
Sample Requirements
Note: Sample amounts are provided for reference only. For detailed information, please contact us with your customized requests.
Our Comprehensive Service
At LC Sciences, we offer a genome-wide microRNA expression profiling service using a microarray detection system developed specifically for microRNA detection. Send us your total RNA sample, and we’ll perform all the necessary steps, from sample QC through data analysis. We can perform microarray analysis on a single sample to create an expression profile, or hybridize two samples on the same microarray for dual-sample analysis. This is especially useful when comparing two samples, such as wild-type vs. mutant, or samples treated in different ways.
Our comprehensive “Total RNA to Data” service includes: sample QC, sample preparation and labeling, microRNA detection (hybridization to a µParaflo® microfluidics chip), array scanning and data extraction, and full data analysis.
Within 2–3 weeks, you will receive: original and processed scan images, the array layout and list of sequences, raw and processed data, a list of differentially expressed transcripts (dual-sample arrays only), and a summary report of the results.
Bioinformatics Analysis Pipeline
DNA Sequencing
LC Sciences provides a variety of fast, comprehensive DNA sequencing solutions, including exome, whole-genome, whole-genome bisulfite, and reduced representation bisulfite sequencing.
Learn MoreMicrobial Sequencing
LC Sciences provides a fast, comprehensive microbial Sequencing solution including: 16S/18S/ITS Amplicon Sequencing, 5R 16S Amplicon Metagenomic Sequencing, Shotgun Metagenomic Sequencing.
Learn MoreRNA Sequencing
LC Sciences offers a range of rapid and comprehensive RNA sequencing solutions, including poly-A RNA, micro RNA, total RNA, circRNA, m6A RNA, and more.
Learn MoreEpigenomics
LC Sciences provides specialized epigenomics services, including Whole Genome Bisulfite Sequencing (comprehensive single-base resolution DNA methylation analysis), Reduced Representation Bisulfite Sequencing (targeted CpG-rich region study with lower cost), ATAC-seq (chromatin accessibility and regulatory element investigation), and CUT&Tag (high-resolution chromatin profiling for small/single-cell samples).
Learn MoreSingle Cell Sequencing
Learn MoreProteomics & Metabolomics
LC Sciences is focused on providing scientific researchers with more minute and precise protein expression-related services, including olink proteomics.
Learn MorePre-made Library Sequencing
Learn MoreAdditional Services
Our portfolio of additional services includes Bioinformatic Services, Oligomix, MicroRNA Profiling Microarray, DNA/RNA Aptamer Microarray, Epitope Mapping, and Kinase Profiling. These services are designed to support various aspects of molecular research and biomolecular analysis, providing comprehensive solutions tailored to your specific scientific needs.
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