Your end-to-end research partner.
Ensuring reliable, publication-ready results.
Poly (A) RNA-Seq is an advanced method for accurately measuring gene expression in biological samples under specific conditions. It enables the identification of novel transcripts, alternative splicing, and gene fusion events, providing a comprehensive view of the transcriptome.
Applications
Differential gene expression screening and functional analysis
Time-course analysis or concentration-gradient analysis
Investigation of upstream regulatory genes
Large-scale sample studies (e.g., cohort studies combined with machine learning)
Poly (A) Sequencing (mRNA-seq) Advantages
Library construction specific to the chain
The library retains directional mRNA information, enabling the acquisition of more accurate and comprehensive transcript data.
Extensive experience
Our clients have published over 1,000 transcriptome studies, including more than 200 publications with a high impact factor (IF>10).
Specialist team
Our team includes experienced professionals who provide support in experimental design and data interpretation.
Reliable and fast turnaround time
A dedicated project manager ensures delivery of results within 20 business days following sample quality verification.
Sample Requirements
Note: Sample quantities are provided for reference only. For detailed information, please contact us with your customized requirements.
Our Comprehensive Service
At LC Sciences, we offer a genome-wide poly(A) sequencing (mRNA-seq) service utilizing a high-throughput sequencing platform optimized for accurate mRNA quantification. Send us your total RNA sample, and we’ll handle all steps from sample QC through data analysis. We can perform mRNA-seq on a single sample to generate a standard expression profile, or process multiple samples with robust normalization for comparative analysis—ideal for studies requiring comparisons such as wild-type versus mutant or samples subjected to different treatments.
Our “Total RNA to Data” comprehensive service includes: Sample QC, Library Preparation and Sequencing, mRNA Detection and Quantification, Data Processing, and Full Data Analysis with standard expression outputs.
With fast turnaround time, you will receive: original and processed scan images, array layout and a list of sequences, raw and processed data, a list of differentially expressed transcripts (dual sample arrays only), and a summary of the results.
Bioinformatics Analysis Pipeline
DNA Sequencing
LC Sciences provides a variety of fast, comprehensive DNA sequencing solutions, including exome, whole-genome, whole-genome bisulfite, and reduced representation bisulfite sequencing.
Learn MoreMicrobial Sequencing
LC Sciences provides a fast, comprehensive microbial Sequencing solution including: 16S/18S/ITS Amplicon Sequencing, 5R 16S Amplicon Metagenomic Sequencing, Shotgun Metagenomic Sequencing.
Learn MoreRNA Sequencing
LC Sciences offers comprehensive RNA sequencing services, including poly(A), microRNA, total RNA, circRNA, and m6A sequencing. LC Sciences RNA-seq services enable accurate and efficient transcriptomic analysis.
Learn MoreEpigenomics
LC Sciences provides specialized epigenomics services, including Whole Genome Bisulfite Sequencing (comprehensive single-base resolution DNA methylation analysis), Reduced Representation Bisulfite Sequencing (targeted CpG-rich region study with lower cost), ATAC-seq (chromatin accessibility and regulatory element investigation), and CUT&Tag (high-resolution chromatin profiling for small/single-cell samples).
Learn MoreSingle Cell Sequencing
As one of the trusted in single cell sequencing companies, our advanced single-cell sequencing services support research in cellular biology and precision medicine, including scRNA-seq, immune profiling, and single-cell ATAC-seq to reveal cellular heterogeneity and deeper biological insights.
Learn MoreProteomics & Metabolomics
LC Sciences is focused on providing scientific researchers with more minute and precise protein expression-related services, including olink proteomics, positioning itself as a reliable proteomics company dedicated to advancing high-quality proteomic research and analysis.
Learn MorePre-made Library Sequencing
Learn MoreAdditional Services
Our portfolio of additional services includes Bioinformatic Services, Oligomix, MicroRNA Profiling Microarray, DNA/RNA Aptamer Microarray, Epitope Mapping, and Kinase Profiling. These services are designed to support various aspects of molecular research and biomolecular analysis, providing comprehensive solutions tailored to your specific scientific needs.
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