
Your end-to-end research partner.
Ensuring reliable, publication-ready results.

Low-Input RNA Sequencing (Smart Pico RNA Sequencing), powered by the SMARTer Stranded Total RNA-Seq Kit v2 - Pico Input Mammalian, is an ultra-sensitive RNA-seq solution specifically designed for challenging samples such as formalin-fixed paraffin-embedded (FFPE) tissues and extremely limited inputs as low as 10 pg. This technology overcomes the limitations of conventional methods regarding sample integrity and input requirements.
Low-Input RNA Sequencing Applications

Transcriptomic analysis of clinical trace/FFPE samples

cfRNA detection in body fluids for liquid biopsy

Exosomal RNA profiling and analysis

Transcriptome profiling of rare functional cells

Trace neuronal subtype analysis in neuroscience
Low-Input RNA Sequencing Advantages

Advanced and Robust Technology
The optimized Smart pico library preparation technology enables accurate processing of trace/degraded RNA from FFPE and biopsy samples, delivering highly reliable data quality.

Complete End-to-End Service
We provide a seamless, all-in-one workflow—from sample extraction and library construction to sequencing and bioinformatics analysis—ensuring a consistent and efficient process.

Expert Team Support
Our experienced technical specialists offer professional guidance throughout the project, from experimental design to data interpretation.

Efficient Project Turnaround
Each project is managed by a dedicated specialist to ensure prompt processing and delivery of results following sample QC, helping you stay on track with your research timeline.
Sample Requirements

Note: Sample amounts are provided for reference only. For detailed information, please contact us with your customized requests.
Low-Input RNA Sequencing Bioinformatics Analysis Pipeline

DNA Sequencing
LC Sciences provides a variety of fast, comprehensive DNA sequencing solutions, including exome, whole-genome, whole-genome bisulfite, and reduced representation bisulfite sequencing.
Learn MoreMicrobial Sequencing
LC Sciences provides a fast, comprehensive microbial Sequencing solution including: 16S/18S/ITS Amplicon Sequencing, 5R 16S Amplicon Metagenomic Sequencing, Shotgun Metagenomic Sequencing.
Learn MoreRNA Sequencing
LC Sciences offers comprehensive RNA sequencing services, including poly(A), microRNA, total RNA, circRNA, and m6A sequencing. LC Sciences RNA-seq services enable accurate and efficient transcriptomic analysis.
Learn MoreEpigenomics
LC Sciences provides specialized epigenomics services, including Whole Genome Bisulfite Sequencing (comprehensive single-base resolution DNA methylation analysis), Reduced Representation Bisulfite Sequencing (targeted CpG-rich region study with lower cost), ATAC-seq (chromatin accessibility and regulatory element investigation), and CUT&Tag (high-resolution chromatin profiling for small/single-cell samples).
Learn MoreSingle Cell Sequencing
As one of the trusted in single cell sequencing companies, our advanced single-cell sequencing services support research in cellular biology and precision medicine, including scRNA-seq, immune profiling, and single-cell ATAC-seq to reveal cellular heterogeneity and deeper biological insights.
Learn MoreProteomics & Metabolomics
LC Sciences is focused on providing scientific researchers with more minute and precise protein expression-related services, including olink proteomics, positioning itself as a reliable proteomics company dedicated to advancing high-quality proteomic research and analysis.
Learn MorePre-made Library Sequencing
Learn MoreAdditional Services
Our portfolio of additional services includes Bioinformatic Services, Oligomix, MicroRNA Profiling Microarray, DNA/RNA Aptamer Microarray, Epitope Mapping, and Kinase Profiling. These services are designed to support various aspects of molecular research and biomolecular analysis, providing comprehensive solutions tailored to your specific scientific needs.
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