From  – BioHouston.org Houston (August 19, 2010) Researchers from LC Sciences LLC and a collaboration of Universities1 have  established a porcine microRNAome, a complete catalog of all microRNAs expressed in the species Sus scrofa2.  MicroRNAs (miRNAs) are small regulatory RNA molecules known to control a wide array of cellular functions such as growth and development […]
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Results blaze a trail for advancement in pig biology as well the use of pigs as model organism for human biological and biomedical studies Houston, TX – (Aug 19, 2010) Researchers from LC Sciences LLC and a collaboration of Universities1 have  established a porcine microRNAome, a complete catalog of all microRNAs expressed in the species […]
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The development of next generation technologies is enabling the complete mapping and further understanding of microRNAs (miRNAs).  Deep sequencing (NGS) provides complete coverage of the small transcriptome and new bioinformatics tools such as ACGT101-miR enable an exhaustive analysis of the sequencing data. The application of these new technologies together with the availability of a nearly […]
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In general, animal microRNA (miRNA) biogenesis involves sequential cleavage of precursor substrates by the Drosha and Dicer enzymes. Although there are several alternative pathways that exploit other RNA metabolic activities to generate functional miRNAs, the fact that all of these pathways culminate in Dicer cleavage has suggested that it is critical to miRNA biogenesis. Now, […]
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LC Sciences has been offering high quality oligonucleotide pools of up to 4000 sequences (OligoMix®) since 2004 for various genomics applications, including gene synthesis. Here the authors not only present a robust, time- and cost-efficient gene assembly protocol for high quality gene assembly directly from OligoMix® oligonucleotides, but they also demonstrate that genes assembled from […]
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The current release of the PepCyber: P~Pep database V1.2 (May 2010) includes 11,269 records of interactions between 387 PPBD proteins and 1,471 substrate proteins, curated from 4,852 published studies.  This release represents a 60% increase in the number proteins covered over the previous release. PepCyber: P~Pep is the largest public database of human protein-protein interactions […]
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InDepth Data Analysis Report Includes: Map to Reference Sequence Includes custom construction of reference database(s) for mapping – miRBase, genome, etc Sequence data can be aligned to any publicly available small RNA databases for annotation of known small RNA Unknown small RNAs can be aligned with reference genomes Additional Bioinformatics Analysis Classification of all mapped […]
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The domestic pig is of enormous agricultural significance and valuable models for many human diseases. Information concerning the pig microRNAome (miRNAome) has been long overdue and elucidation of this information will permit an atlas of microRNA (miRNA) regulation functions and networks to be constructed. Here we performed a comprehensive search for porcine miRNAs on ten […]
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Please nte that the sample submission form for microRNA Microarray Service has been updated due to the update of miRBase to version 15.  If you have a previous version of the form saved locally, please replace with this new form.  Click the link below or visit www.lcsciences.com to download the form. Thank You
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