Scientists Scrutinize Promising Molecules as Potential Drug Targets and Biomarkers Genetic Engineering News – Patricia F. Dimond, Ph.D. MicroRNAs (miRNAs) finely regulate gene expression and play an important role in various cellular processes, including cell growth, differentiation, proliferation, and apoptosis. To date, more than 5,000 of these endogenous, noncoding single-stranded RNAs have been identified. miRNAs […]
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Presentations: From Worms to Humans: Understanding the Role of miRNAs in Cancer Progression Aurora Esquela-Kerscher, Ph.D., Assistant Professor, Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School miRNAs regulate important developmental events and are often misexpressed in human cancers, but little is known regarding how these molecules contribute to tumor formation. Our laboratory […]
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Seq-Array
March 19, 2010 – Houston, TX -LC Sciences today announced the launch of its new Seq-ArraySM services designed to take full advantage of both the latest deep sequencing capabilities and the proven genomics tool – microarray. This combination of technologies advances microRNA research to the next level of depth and understanding that was not possible […]
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Press Release
Houston (PRWEB) March 19, 2010 — LC Sciences today announced the launch of its new Seq-Array services designed to take full advantage of both the latest deep sequencing capabilities and the proven genomics tool – microarray. This combination of technologies advances microRNA research to the next level of depth and understanding that was not possible […]
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Seq-ArraySM offers a customized solution to high-throughput genome-wide miRNA discovery and profiling, especially in species with limited or no miRNA sequence information available. This unique combination of the latest deep sequencing technology, advanced bioinformatics, and our innovative µParaflo® custom microarray platform leverages all these technologies to form a comprehensive service package tailored to your specific […]
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by Jeffrey M. Perkel Once the domain of microarrays – the previous decade’s hot technology — transcriptome analysis (that is, gene expression monitoring on a genome-wide scale) is now associated with the current “it” technology: Next-generation DNA sequencing. Though such data can be collected using arrays (sequencing was previously used mostly for transcript discovery), with […]
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As high-throughput techniques accelerate mapping of epigenetic marks, researchers are racing to find the biological meaning of these marks. Thanks to the Human Genome Project, researchers worldwide can search a database to see what a gene ‘says’. In just a few years, researchers may also be able to look up when a gene is ‘read’. […]
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Frank Breitling1 , Christopher Schirwitz2, Thomas Felgenhauer2, Ines Block2, Volker Stadler2 and Ralf Bischoff2 (1)  Karlsruhe Institute of Technology, Helmholtzplatz 1, 76344 Eggenstein-Leopoldshafen, Germany (2)  AG Chipbasierte Peptidbibliotheken, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany   Affordable high-density peptide arrays are needed to routinely define the exact binding sites of antibodies. In terms of prize and density peptide arrays currently lag far behind oligonucleotide […]
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3/22/10 – 3/24/10  Boston, MA TOPICS INCLUDE: microRNA in Cancer microRNA in Biomarker and Diagnostic Development microRNA in Therapeutic Development microRNA in Human Development and Disease microRNA Pathways and Mechanisms Don’t miss the Technology Showcase Wed 3/24/10 12:35-12:50 Seq-Array – miRNA Discovery and Profiling Using a Customizable Workflow Christoph Eicken, Ph.D., Head of Technical Services – […]
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Here is the latest list of publications from our customers making use of our microRNA Discovery and Profiling Services.  The current list includes more than 140 publications by some of the leading researchers in the microRNA field.  Enjoy!
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