A transposable element (TE) is a DNA fragment that can change its position within a genome. Transposable elements play important roles in maintaining the stability and diversity of organisms by transposition. Recent studies have shown that approximately half of the genes in Bombyx mori are TEs...
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SFN 2017
SfN’s 47th annual meeting, Neuroscience 2017, is the world’s largest neuroscience conference for scientists and physicians devoted to understanding the brain and nervous system. Neuroscience 2017 is November 11-15 at the Walter E. Washington Convention Center. Join more than 30,000 colleagues from more than 80 countries at the world’s largest marketplace of ideas and tools […]
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The AACR Annual Meeting 2017 will be held at the Walter E. Washington Convention Center in Washington, D.C., from April 1-5, with exhibit dates April 2-5. The AACR Annual Meeting highlights the best cancer science and medicine from institutions all over the world. Attendees are invited to stretch their boundaries, form collaborations, attend sessions outside […]
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Indole-3-butyric acid (IBA) is applied to the cuttings of various plant species to induce formation of adventitious roots (ARs) in commercial settings. Tetraploid black locust is an attractive ornamental tree that is drought resistant, sand tolerant, can prevent sand erosion and has various commercial uses. To further elucidate the mechanisms of AR formation, researchers from Northwest A&F University used RNA sequencing to analyze transcriptome dynamics and differential gene expression at four developmental stages in control (CK) and IBA-treated groups...
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Cervical cancer (CC) is the second most common cancer in females in developing countries. The two viral oncoproteins E6 and E7 mediate the oncogenic activities of high-risk human papillomavirus (HR-HPV), and HR-HPV, especially HPV16 or/and HPV18 (HPV16/18) play critical roles in CC through different pathways. microRNAs (miRNAs) may be associated with CC pathogenesis. Researches have indicated that human papillomavirus (HPV) may regulate cellular miRNA expression through viral E6 and E7...
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MicroRNAs (miRNAs) are a group of endogenous non-coding small RNAs that have critical regulatory functions in almost all known biological processes at the post-transcriptional level in a variety of organisms. The oriental fruit moth Grapholita molesta is one of the most serious pests in orchards worldwide and threatens the production of Rosacea fruits...
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Researchers in the field of mitochondrial biology are increasingly unveiling of the complex mechanisms between mitochondrial dysfunction and noncoding RNAs (ncRNAs). However, roles of ncRNAs underlying mitochondrial myopathy remain unexplored. The aim of a recent study led by researchers from Shandong University sought to elucidate the regulating networks of dysregulated ncRNAs in Mitochondrial myopathy, Encephalopathy, Lactic Acidosis, and Stroke-like episodes (MELAS) with mitochondrial DNA (mtDNA) A3243G mutation...
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MicroRNAs (miRNAs) are a class of endogenous, evolutionarily conserved small non-coding RNA molecules that mediate the posttranscriptional processing of target genes, leading to translational repression or degradation of target mRNAs. A series of studies have indicated that miRNAs play an important role in tumor initiation, development and progression. In a recent study led by researchers from Shanghai Jiao Tong University School of Medicine, they found that down regulation of miR-598 was a frequent event in CRC tissues compared to the paracarcinoma tissues. Their study also demonstrated that miR-598 was implicated in CRC metastasis...
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miR1444s are functionally significant miRNAs targeting polyphenol oxidase (PPO) genes for cleavage and MIR1444 genes have only been reported in Populus trichocarpa. Through computational analysis of RNA-seq data, four whole genome sequences of Salicaceae species and small RNA deep sequencing of six P. trichocarpa libraries, researchers from Peking Union Medical College investigated the origin and evolution history of these MIR1444 genes...
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Leukoencephalopathies are a group of white matter disorders related to abnormal formation, maintenance, and turnover of myelin in the central nervous system. These disorders of the brain are categorized according to neuroradiological and pathophysiological criteria. In a recent study, a team led by researchers from Galilee Medical Center identified a unique form of leukoencephalopathy in seven patients presenting at ages 2 to 4 months with progressive microcephaly, spastic quadriparesis, and global developmental delay...
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