MicroRNA (miRNA) are small noncoding RNA that help regulate gene expression and metabolic function. Some miRNA, called MyomiR, are expressed predominately in skeletal muscle and regulate myogenesis. The objective of a recent study by a researcher from Clemson University sought to identify miRNA in skeletal muscle of fetuses exposed to ergot alkaloids in utero...
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MicroRNA is known to be an important regulator of gene expression. Researchers from Chonnam National University Medical School, Korea selected microRNAs that were found to be differentially expressed in normal urothelium and urothelial carcinomas in the literature. microRNAs identified ny microarray in two expression profiling studies conducted by LC Science customers...
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lc sciences
Oleocellosis is a serious physiological disorder in citrus fruit that mainly results in appearance and quality deterioration. It has been well established that the occurrence of oleocellosis is highly correlated with the release of peel oil from citrus fruit, but there is little information on the dynamic changes in the content of volatile constituents and expression of genes involved in terpenoid metabolism during oleocellosis development...
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LC Sciences
Understanding the metabolic and gene expression changes that accompany the expression of Yellow Canopy Syndrome (YCS) in sugarcane is important and could greatly assist in developing management strategies as well as in the identification of potential causal factors.
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Pyropia yezoensis is commonly known as a valuable marine red alga. As a cold-temperate species, high temperature is a critical abiotic stress factor that can affect the growth and development of this seaweed. Exploring the regulatory mechanisms of P. yezoensis resistance to high temperatures has significance in breeding high temperature-resistant strains...
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Spiroplasma eriocheiris is a novel pathogen similar to the Spiroplasma mirum and also had an ability to infect the newborn mice and caused cataract. A study by scientists from Nanjing Normal University was designed to study how S. eriocheiris infects mouse 3T6-Swiss albino cells and to elucidate the cellular molecular pathogenesis of Spiroplasma...
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Under natural conditions, some embryos cannot implant successfully because of the dysfunction of receptive endometrium (RE). Thus, it is imperative to study the molecular mechanisms involved in the formation of RE from pre-receptive endometrium (PE). In a recent study, researchers from Northwest A&F University collected endometrium from gestational day 5 (D5, PE) and gestational day 15 (D15, RE) dairy goats to analyze the transcriptome using strand-specific total RNA-Seq...
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Consuming ergot alkaloids found in endophyte-infected tall fescue seed causes intrauterine growth restriction due to uteroplacental insufficiency. The objective of a recent study by scientists from Clemson University was to assess the impact on gene expression levels in placental tissue from feeding ergot alkaloids during gestation...
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To understand the role of miRNAs in regulating genes involved in the host response to Salmonella enteritidis (SE) infection, next generation sequencing was applied to explore the altered splenic expression of microRNAs (miRNAs) and deregulated genes in specific-pathogen-free chickens. In the study by researchers from the Chinese Academy of Agricultural Sciences, birds were either infected or not (controls, C) and those challenged with SE were evaluated 24 h later and separated into two groups on the basis of the severity of clinical symptoms and blood load of SE...
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Rapid and efficient methods for the determination of cured pulmonary tuberculosis (TB) are lacking. Researchers from Zhejiang University screened serum miRNAs using miRNA sequencing methods among untreated TB patients, two-month treated TB patients, cured TB patients, and healthy controls...
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