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To date, numerous microRNAs (miRNAs) have been discovered from various organisms, including mammals, plants, insects, nematodes and viruses. They are known to have antiviral functions in crustaceans such as shrimp Marsupenaeus japonicas. However, little is known about the role of miRNAs against bacterial infection in this shrimp caused by Vibrio alginolyticus. In a recent report […]
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hepatitis-s1-liver-hepatitis-virus
Circulating miRNAs, a family of miRNAs existing in plasma and serum, have a great potential to serve as novel biomarkers in body fluids for non-invasive diagnosis and prognosis of many diseases. Researchers from Jiangsu University recently designed a multistage, case-control study to establish a panel of serum miRNAs that could be surrogate markers for chronic […]
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Recently, LC Sciences traveled to Baltimore, to take part in the American Society of Human Genetics Annual Meeting. The meeting provides a forum for the presentation and discussion of cutting-edge science in all areas of human genetics: at platform and poster sessions; on the trade show floor; and at interactive workshops and events. The largest […]
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stem
The ability of mouse embryonic stem cells (mESCs) to self-renew or differentiate into various cell lineages is regulated by signaling pathways and a core pluripotency transcriptional network (PTN) comprising Nanog, Oct4, and Sox2. The Wnt/β-catenin pathway promotes pluripotency by alleviating T cell factor TCF3-mediated repression of the PTN. However, it has remained unclear how β-catenin’s […]
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Aphis gossypii 1
Resistance to Aphis gossypii in melon is attributed to the presence of the single dominant R gene Vat, which is biologically expressed as antibiosis, antixenosis, and tolerance. However, the mechanism of resistance is poorly understood at the molecular level. Aphid-induced transcriptional changes, including differentially expressed miRNA profiles that correspond to resistance interaction have been reported […]
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hydrothermal
Deep-sea hydrothermal vent shrimp Rimicaris exoculata is a dominant species aggregating in vent fields along the Mid-Atlantic Ocean Ridge. MicroRNAs play important roles in life cycles of eukaryotes. However, little is known about miRNAs of vent animals. One of the significant advantages of next-gen sequencing over microarrays is the ability to perform expression profiling on […]
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UT Southwestern
Event: S3 Vendor Show – University of Texas Southwestern / Rusty Taco – Dallas Date: December 3, 2015 Show Hours: 8:30 – 10:30 AM Location: The Rusty Taco Address: 5350 Harry Hines Blvd, Dallas, TX 75235; (map) UT Southwestern is an academic medical center, world-renowned for its research, widely respected for its teaching and training, and highly […]
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rapeseed-crop
MicroRNAs (miRNAs) are a class of noncoding small RNAs (sRNAs) that play many roles in plant growth, development, and the stress response. Recently, the Brassica napus (B. napus) genome was reported, which allows the genome-wide identification of miRNAs and their targets in B. napus cv. Westar and its transgenic cultivar. To investigate the expression of […]
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TAMU HSC
Event: S3 Vendor Show – Texas A&M HSC Biomedical Sciences / Baylor College of Dentistry – Dallas Date: December 2, 2015 Show Hours: 11:00AM – 1:00 PM Location: 4th Floor Library Address: 3302 Gaston Ave, Dallas, TX 75246; (map) As a distinguished resource for dental education in Texas for more than 100 years, Texas A&M University […]
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MD-Anderson
A recent study led by researchers from Peking Union Medical College aimed to identify microRNAs (miRNAs) from bone marrow mesenchymal stem cells (BMSCs) in a rat model of steroid-induced osteonecrosis of the femoral head (ONFH). Following identification of miRNAs using LC Sciences’ miRNA microarray service, investigators sought to elucidate the molecular mechanisms underlying steroid‑induced ONFH. […]
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