Decline of transcription factor FoxN1, which predominantly regulates thymic epithelial cell (TEC) differentiation and homeostasis lifelong, is demonstrated to be casually related to age-related thymic involution. Whereas, a global role of microRNAs (miRNAs) has also been demonstrated to control and maintain TEC-constituting thymic microenvironment and to be changed in expression profile in the aged thymus...
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Researchers from Dalian Medical University previously reported that excess retinoic acid (RA) resulted in hypoplastic and derangement of myofilaments in embryonic tongue by inhibiting myogenic proliferation and differentiation through CamKIID pathway. Their further studies revealed that the expression of a series of miRNAs was altered by RA administration in embryonic tongue as well as in C2C12 cells...
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PAG 2017
When: January 14-18, 2017 Where: Town & Country Hotel & Convention Center – San Diego, CA The Plant and Animal Genome XXIV Conference is designed to provide a forum on recent developments and future plans for plant and animal genome projects. Consisting of technical presentations, poster sessions, exhibits and workshops, the conference is an excellent […]
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miRNAs are small non-coding regulatory RNAs that play key roles in diverse biological processes. A recent study led by researchers from Northwest A&F University used miRNA sequencing service to profile miRNAs in breeder cock testes to illustrate their functions...
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Broodiness, a maternal behavior and instinct for natural breeding in poultry, inhibits egg production and affects the poultry industry. Phenotypic and physiological factors influencing broodiness in poultry have been extensively studied, but the molecular regulation mechanism of broodiness remains unclear. Effective research strategies focusing on broodiness are hindered by limited understanding of goose developmental biology...
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MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate signal transduction, development, metabolism, and stress responses in plants through post-transcriptional degradation and/or translational repression of target mRNAs. Several studies have addressed the role of miRNAs in model plant species, but miRNA expression and function in economically important forage crops, such as Bouteloua gracilis (Poaceae), a high-quality and drought-resistant grass distributed in semiarid regions of the United States and northern Mexico remain unknown...
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Wood formation is a complex developmental process primarily controlled by a regulatory transcription network. MicroRNAs (miRNAs) can modulate the expression of target genes involved in plant growth and development by inducing mRNA degradation and translational repression. In a recent study, a team led by researchers from the Chinese Academy of Forestry used a model of secondary vascular system regeneration established in Populus tomentosa to harvest differentiating xylem tissues over time for high-throughput sequencing of small RNAs...
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A team of researchers from Auburn University recently sought to examine potential amino acid independent mechanisms whereby hydrolyzed whey protein (WP) affects muscle protein synthesis (MPS) and anabolism in vitro. Specifically, they tested (1) whether 3-h and 6-h treatments of WP, essential amino acids, or l-leucine (Leu) affected MPS, and whether 6-h treatments with low-, medium-, or high doses of WP versus Leu affected MPS...
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sfn 2016
SfN’s 46th annual meeting is the premier venue for neuroscientists to present emerging science, learn from experts, collaborate with peers, explore new tools and technologies, and advance careers. Neuroscience 2016 will take place November 12-16 at the San Diego Convention Center. Join more than 30,000 colleagues from more than 80 countries at the world’s largest marketplace […]
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MicroRNAs in eukaryotic cells are thought to control highly complex signal transduction and other biological processes by regulating coding transcripts, accounting for their important role in cellular events in eukaryotes. Recently, a novel class of bacterial RNAs similar in size [18–22 nucleotides (nt)] to microRNAs has been reported. In a recent study, researchers from Kyungpook National University describe microRNAs, small RNAs from the oral pathogen Streptococcus sanguinis. The bacteria are normally present in the oral cavities and cause endocarditis by contaminating bloodstreams...
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