The 16S rRNA gene is a highly conserved component of the transcriptional machinery of all DNA-based life forms and thus is highly suited as a target gene for sequencing DNA in samples containing up to thousands of different species. 16S rRNA gene sequencing is commonly used for identification, classification and quantitation of microbes in complex biological mixtures such as environmental samples like water, soil or air, and microbiome samples such as milk or feces...
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Vasoactive liabilities are typically assayed using wire myography, which is limited by its high cost and low throughput. To meet the demand for higher throughput in vitro alternatives, researchers from Nano3D Biosciences, LC Sciences, and AstraZeneca introduced a magnetic 3D bioprinting-based vasoactivity assay. The principle...
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MicroRNAs (miRNAs) play a pivotal role in the development of liver fibrosis. However, the functions of miRNAs in hepatitis C virus (HCV)-related liver fibrosis remain unclear. In this study, researchers from Hebei Medical University and the Bethune International Peace Hospital systematically analyzed the microarray data of the serum miRNAs in patients with HCV-induced hepatic fibrosis...
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Thyroid cancer is one of the most common carcinomas of the endocrine system with an increasing incidence. A growing number of studies have focused on the diagnostic and prognostic values of dysregulated microRNAs (miRNAs) in thyroid carcinoma. However, differences in the measurement platforms, variations in lab protocols, and small sample sizes can make gene profiling data incomparable...
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“This assay is the only one of its kind on the market that can replace animal testing for vasoactivity studies. This assay not only addresses an unmet need in this space, but also highlights our versatility and innovation of n3D’s magnetic 3D bioprinting technology. We are excited to have a new tool for CROs and […]
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Similar to the incredible advances in DNA sequencing, the de novo synthesis of DNA is subject to innovations and fast progress in terms of synthesis speed and cost. Researchers from the Thermo Fisher Scientific Inc. discuss novel techniques that are expected to enable high-throughput synthesis of oligonucleotides on microarrays and the subsequent assembly into longer fragments, up to whole genomes...
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MicroRNAs (miRNAs) play an important role in plant growth, development, and response to environment. For identifying and comparing miRNAs and their targets in seed development between two maize inbred lines...
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lc Sciences
MicroRNAs (miRNAs) are noncoding RNA molecules that regulate gene expression at the post-transcriptional level to cause translational repression or degradation of targets. The profiles of miRNAs across stages of lactation in small ruminant species such as dairy goats is unknown...
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MicroRNAs (miRNAs) are a class of endogenous small non-coding RNAs that regulate various biological processes including sexual dimorphism. The oriental fruit fly Bactrocera dorsalis is one of the most destructive agricultural insect pests in many Asian countries. However, no miRNAs have been identified from the separate sex and gonads to elucidate sex gonad differentiation in B. dorsalis...
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Radiation-induced bystander effect (RIBE) describes a set of biological effects in non-targeted cells that receive bystander signals from the irradiated cells. RIBE brings potential hazards to adjacent normal tissues in radiotherapy, and imparts a higher risk than previously thought. Excessive release of some substances from irradiated cells into extracellular microenvironment has a deleterious effect...
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